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RNAi-Mediated Specific Gene Silencing as a Tool for the Discovery of New Drug Targets in Giardia lamblia; Evaluation Using the NADH Oxidase Gene

The microaerophilic protozoan Giardia lamblia is the agent causing giardiasis, an intestinal parasitosis of worldwide distribution. Different pharmacotherapies have been employed against giardiasis; however, side effects in the host and reports of drug resistant strains generate the need to develop...

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Detalles Bibliográficos
Autores principales: Marcial-Quino, Jaime, Gómez-Manzo, Saúl, Fierro, Francisco, Rufino-González, Yadira, Ortega-Cuellar, Daniel, Sierra-Palacios, Edgar, Vanoye-Carlo, America, González-Valdez, Abigail, Torres-Arroyo, Angélica, Oria-Hernández, Jesús, Reyes-Vivas, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704216/
https://www.ncbi.nlm.nih.gov/pubmed/29099754
http://dx.doi.org/10.3390/genes8110303