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LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-β-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway

Retinal pigment epithelial (RPE) cells have crucial roles in the initiation and development of human ophthalmic diseases. Our previous study suggested that transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) is a potential target in the progression and pathogenesis of human proliferative...

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Detalles Bibliográficos
Autores principales: Chen, Zhen, Ni, Ninghua, Mei, Yan, Yang, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704344/
https://www.ncbi.nlm.nih.gov/pubmed/29201199
http://dx.doi.org/10.3892/etm.2017.5187