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Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails

BACKGROUND: Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein–protein contacts between integrase and histones may be inv...

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Detalles Bibliográficos
Autores principales: Benleulmi, Mohamed S., Matysiak, Julien, Robert, Xavier, Miskey, Csaba, Mauro, Eric, Lapaillerie, Delphine, Lesbats, Paul, Chaignepain, Stéphane, Henriquez, Daniel R., Calmels, Christina, Oladosu, Oyindamola, Thierry, Eloïse, Leon, Oscar, Lavigne, Marc, Andreola, Marie-Line, Delelis, Olivier, Ivics, Zoltán, Ruff, Marc, Gouet, Patrice, Parissi, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704366/
https://www.ncbi.nlm.nih.gov/pubmed/29179726
http://dx.doi.org/10.1186/s12977-017-0378-x