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Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
BACKGROUND: Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein–protein contacts between integrase and histones may be inv...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704366/ https://www.ncbi.nlm.nih.gov/pubmed/29179726 http://dx.doi.org/10.1186/s12977-017-0378-x |