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Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells

BACKGROUND: Chemotherapeutic drugs used for cancer therapy frequently encounter multiple-drug resistance (MDR). Nanoscale carriers that can target tumors to accumulate and release drugs intracellularly have the greatest potential for overcoming MDR. Glucose transporter-1 (GLUT-1) and glutathione (GS...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Wen, Huaying, Gu, Liang, Fu, Jijun, Guo, Jiayi, Du, Lingran, Zhou, Xiaoqin, Yu, Xiyong, Huang, Yugang, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704373/
https://www.ncbi.nlm.nih.gov/pubmed/29179722
http://dx.doi.org/10.1186/s12951-017-0316-z