Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Liquid–liquid phase separation (LLPS) is thought to contribute to the establishment of many biomolecular condensates, eukaryotic cell structures that concentrate diverse macromolecules but lack a bounding membrane. RNA granules control RNA metabolism and comprise a large class of condensates that ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yuan, Currie, Simon L., Rosen, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704491/
https://www.ncbi.nlm.nih.gov/pubmed/28924037
http://dx.doi.org/10.1074/jbc.M117.800466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704491/
https://www.ncbi.nlm.nih.gov/pubmed/28924037
http://dx.doi.org/10.1074/jbc.M117.800466

Ejemplares similares