Cargando…

Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization

BACKGROUND: Neuroinflammation, which ultimately leads to neuronal loss, is considered to play a crucial role in numerous neurodegenerative diseases. The neuroinflammatory process is characterized by the activation of glial cells such as microglia. Endoplasmic reticulum (ER) stress is commonly associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yi-wei, Zhou, Qin, Zhang, Xiang, Qian, Qing-qing, Xu, Jia-wen, Ni, Peng-fei, Qian, Yan-ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704515/
https://www.ncbi.nlm.nih.gov/pubmed/29179727
http://dx.doi.org/10.1186/s12974-017-1002-7