Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology

Although the formation of β-amyloid (Aβ) fibrils in neuronal tissues is a hallmark of Alzheimer disease (AD), small-sized Aβ oligomers rather than mature fibrils have been identified as the most neurotoxic species. Therefore, the design of new inhibitors, able to prevent the aggregation of Aβ, is be...

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Detalles Bibliográficos
Autores principales: Galati, Clelia, Spinella, Natalia, Renna, Lucio, Milardi, Danilo, Attanasio, Francesco, Sciacca, Michele Francesco Maria, Bongiorno, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704750/
https://www.ncbi.nlm.nih.gov/pubmed/29234579
http://dx.doi.org/10.3762/bjnano.8.243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704750/
https://www.ncbi.nlm.nih.gov/pubmed/29234579
http://dx.doi.org/10.3762/bjnano.8.243

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