Inferior immunogenicity and efficacy of respiratory syncytial virus fusion protein-based subunit vaccine candidates in aged versus young mice

Respiratory syncytial virus (RSV) is recognized as an important cause of lower and upper respiratory tract infections in older adults, and a successful vaccine would substantially lower morbidity and mortality in this age group. Recently, two vaccine candidates based on soluble purified glycoprotein...

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Detalles Bibliográficos
Autores principales: Cayatte, Corinne, Snell Bennett, Angie, Rajani, Gaurav Manohar, Hostetler, Leigh, Maynard, Sean K., Lazzaro, Michelle, McTamney, Patrick, Ren, Kuishu, O’Day, Terrence, McCarthy, Michael P., Schneider-Ohrum, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705161/
https://www.ncbi.nlm.nih.gov/pubmed/29182682
http://dx.doi.org/10.1371/journal.pone.0188708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705161/
https://www.ncbi.nlm.nih.gov/pubmed/29182682
http://dx.doi.org/10.1371/journal.pone.0188708

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