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A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics

How left-right patterning drives asymmetric morphogenesis is unclear. Here, we have quantified shape changes during mouse heart looping, from 3D reconstructions by HREM. In combination with cell labelling and computer simulations, we propose a novel model of heart looping. Buckling, when the cardiac...

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Detalles Bibliográficos
Autores principales: Le Garrec, Jean-François, Domínguez, Jorge N, Desgrange, Audrey, Ivanovitch, Kenzo D, Raphaël, Etienne, Bangham, J Andrew, Torres, Miguel, Coen, Enrico, Mohun, Timothy J, Meilhac, Sigolène M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705212/
https://www.ncbi.nlm.nih.gov/pubmed/29179813
http://dx.doi.org/10.7554/eLife.28951