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A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics
How left-right patterning drives asymmetric morphogenesis is unclear. Here, we have quantified shape changes during mouse heart looping, from 3D reconstructions by HREM. In combination with cell labelling and computer simulations, we propose a novel model of heart looping. Buckling, when the cardiac...
Autores principales: | Le Garrec, Jean-François, Domínguez, Jorge N, Desgrange, Audrey, Ivanovitch, Kenzo D, Raphaël, Etienne, Bangham, J Andrew, Torres, Miguel, Coen, Enrico, Mohun, Timothy J, Meilhac, Sigolène M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705212/ https://www.ncbi.nlm.nih.gov/pubmed/29179813 http://dx.doi.org/10.7554/eLife.28951 |
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