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β(2)-Adrenoceptor Blockade Deteriorates Systemic Anaphylaxis by Enhancing Hyperpermeability in Anesthetized Mice

PURPOSE: Patients treated with propranolol, a nonselective β-adrenoceptor antagonist, develop severe anaphylaxis, but the mechanism remains unknown. We determined effects of β(1)- and β(2)-adrenoceptor antagonists on the anaphylaxis-induced increase in vascular permeability in mice. METHODS: In anes...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Shibamoto, Toshishige, Kuda, Yuhichi, Zhang, Tao, Tanida, Mamoru, Kurata, Yasutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705484/
https://www.ncbi.nlm.nih.gov/pubmed/29178678
http://dx.doi.org/10.4168/aair.2018.10.1.52