Promoter Specificity and Efficacy in Conditional and Inducible Transgenic Targeting of Lung Macrophages

Conditional and inducible Cre-loxP systems are used to target gene deletion to specific cell lineages and tissues through promoter-restricted expression of the bacterial DNA recombinase, Cre. Although Cre-loxP systems are widely used to target gene deletion in lung macrophages, limited data are publ...

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Detalles Bibliográficos
Autores principales: McCubbrey, Alexandra L., Allison, Kristen C., Lee-Sherick, Alisa B., Jakubzick, Claudia V., Janssen, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705560/
https://www.ncbi.nlm.nih.gov/pubmed/29225599
http://dx.doi.org/10.3389/fimmu.2017.01618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705560/
https://www.ncbi.nlm.nih.gov/pubmed/29225599
http://dx.doi.org/10.3389/fimmu.2017.01618

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