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Thyroid hormones derivatives reduce proliferation and induce cell death and DNA damage in ovarian cancer

Ovarian cancer is a highly aggressive disease and novel treatments are required. Thyroid hormones binding to αvβ3 integrin produced growth-promoting activities in ovarian cancer and we hypothesized that natural thyroid hormone derivatives may antagonize these actions. The effect of three antagonists...

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Detalles Bibliográficos
Autores principales: Shinderman-Maman, Elena, Cohen, Keren, Moskovich, Dotan, Hercbergs, Aleck, Werner, Haim, Davis, Paul J., Ellis, Martin, Ashur-Fabian, Osnat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705594/
https://www.ncbi.nlm.nih.gov/pubmed/29184090
http://dx.doi.org/10.1038/s41598-017-16593-x