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Thyroid hormones derivatives reduce proliferation and induce cell death and DNA damage in ovarian cancer
Ovarian cancer is a highly aggressive disease and novel treatments are required. Thyroid hormones binding to αvβ3 integrin produced growth-promoting activities in ovarian cancer and we hypothesized that natural thyroid hormone derivatives may antagonize these actions. The effect of three antagonists...
Autores principales: | Shinderman-Maman, Elena, Cohen, Keren, Moskovich, Dotan, Hercbergs, Aleck, Werner, Haim, Davis, Paul J., Ellis, Martin, Ashur-Fabian, Osnat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705594/ https://www.ncbi.nlm.nih.gov/pubmed/29184090 http://dx.doi.org/10.1038/s41598-017-16593-x |
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