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All-trans retinoic acid enhances cytotoxicity of CIK cells against human lung adenocarcinoma by upregulating MICA and IL-2 secretion

To determine the growth inhibition capability of all-trans retinoic acid (ATRA) with cytokine-induced killer cells (CIKs), we evaluated their effects, alone and in combination, on human lung carcinoma A549 cells. CIKs treated with ATRA significantly inhibited cell growth. Additionally, CIK with ATRA...

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Detalles Bibliográficos
Autores principales: Fan, Xiao-yan, Wang, Peng-yu, Zhang, Chao, Zhang, Yu-long, Fu, Yun, Zhang, Cong, Li, Qiao-xia, Zhou, Jie-na, Shan, Bao-en, He, Dong-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705634/
https://www.ncbi.nlm.nih.gov/pubmed/29184163
http://dx.doi.org/10.1038/s41598-017-16745-z