2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2

Hepatotoxicity induced by medicinal herb Polygonum multiflorum Thunb. attracts wide attention in the world recently. 2,3,4′,5-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) is a main active compound in Polygonum multiflorum Thunb. This study aims to observe TSG-provided the aggravation on acetaminophe...

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Detalles Bibliográficos
Autores principales: Xu, Shangfu, Liu, Jie, Shi, Jingshan, Wang, Zhengtao, Ji, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705655/
https://www.ncbi.nlm.nih.gov/pubmed/29184146
http://dx.doi.org/10.1038/s41598-017-16688-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705655/
https://www.ncbi.nlm.nih.gov/pubmed/29184146
http://dx.doi.org/10.1038/s41598-017-16688-5

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