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Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface
Antibiotic efflux is one of the most critical mechanisms leading to bacterial multidrug resistance. Antibiotics are effluxed out of the bacterial cell by a tripartite efflux pump, a complex machinery comprised of outer membrane, periplasmic adaptor, and inner membrane protein components. Understandi...
Autores principales: | López, Cesar A., Travers, Timothy, Pos, Klaas M., Zgurskaya, Helen I., Gnanakaran, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705723/ https://www.ncbi.nlm.nih.gov/pubmed/29184094 http://dx.doi.org/10.1038/s41598-017-16497-w |
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