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A novel G-quadruplex motif in the Human MET promoter region

It is known that the guanine-rich strands in proto-oncogene promoters can fold into G-quadruplex structures to regulate gene expression. An intramolecular parallel G-quadruplex has been identified in MET promoter. It acts as a repressor in regulating MET expression. However, the full guanine-rich re...

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Detalles Bibliográficos
Autores principales: Yan, Jing, Zhao, Deming, Dong, Liping, Pan, Shuang, Hao, Fengjin, Guan, Yifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705779/
https://www.ncbi.nlm.nih.gov/pubmed/29054971
http://dx.doi.org/10.1042/BSR20171128