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A simulation model of neuroprogenitor proliferation dynamics predicts age-related loss of hippocampal neurogenesis but not astrogenesis
Adult hippocampal neuroprogenitors give rise to both neurons and astrocytes. As neuroprogenitors are lost with increased age, neurogenesis concomitantly decreases. However, the dynamics of neuron and astrocyte generation throughout adulthood has not been systematically examined. Here, we analyzed th...
Autores principales: | Beccari, Sol, Valero, Jorge, Maletic-Savatic, Mirjana, Sierra, Amanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705784/ https://www.ncbi.nlm.nih.gov/pubmed/29184142 http://dx.doi.org/10.1038/s41598-017-16466-3 |
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