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A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimer's disease

Late onset Alzheimer's disease (AD) is a multifactorial disorder, with AD risk influenced by both environmental and genetic factors. Recent genome-wide association studies (GWAS) have identified genetic loci associated with increased risk of developing AD. The MS4A (membrane-spanning 4-domains...

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Detalles Bibliográficos
Autores principales: Lacher, Sarah E., Alazizi, Adnan, Wang, Xuting, Bell, Douglas A., Pique-Regi, Roger, Luca, Francesca, Slattery, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705802/
https://www.ncbi.nlm.nih.gov/pubmed/29179108
http://dx.doi.org/10.1016/j.redox.2017.10.018