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Mitochondrial DNA density homeostasis accounts for a threshold effect in a cybrid model of a human mitochondrial disease
Mitochondrial dysfunction is involved in a wide array of devastating diseases, but the heterogeneity and complexity of the symptoms of these diseases challenges theoretical understanding of their causation. With the explosion of omics data, we have the unprecedented opportunity to gain deep understa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705840/ https://www.ncbi.nlm.nih.gov/pubmed/29079678 http://dx.doi.org/10.1042/BCJ20170651 |