Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis

BACKGROUND: The onset of seropositive rheumatoid arthritis (RA) is preceded by the presence of specific autoantibodies in the absence of synovial inflammation. Only a subset of these at-risk individuals will develop clinical disease. This impedes efforts to implement early interventions that may pre...

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Detalles Bibliográficos
Autores principales: Tak, Paul P, Doorenspleet, Marieke E, de Hair, Maria J H, Klarenbeek, Paul L, van Beers-Tas, Marian H, van Kampen, Antoine H C, van Schaardenburg, Dirkjan, Gerlag, Danielle M, Baas, Frank, de Vries, Niek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705849/
https://www.ncbi.nlm.nih.gov/pubmed/28790026
http://dx.doi.org/10.1136/annrheumdis-2017-211351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705849/
https://www.ncbi.nlm.nih.gov/pubmed/28790026
http://dx.doi.org/10.1136/annrheumdis-2017-211351

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