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Predicting and managing primary and secondary non-response to rituximab using B-cell biomarkers in systemic lupus erythematosus

OBJECTIVE: To assess factors associated with primary and secondary non-response to rituximab in systemic lupus erythematosus (SLE) and evaluate management of secondary non-depletion non-response (2NDNR). METHODS: 125 patients with SLE treated with rituximab over 12 years were studied prospectively....

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Detalles Bibliográficos
Autores principales: Md Yusof, Md Yuzaiful, Shaw, Daniel, El-Sherbiny, Yasser M, Dunn, Emma, Rawstron, Andy C, Emery, Paul, Vital, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705851/
https://www.ncbi.nlm.nih.gov/pubmed/28684557
http://dx.doi.org/10.1136/annrheumdis-2017-211191