The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers

Cancer therapies are associated with increased infertility risk due to accelerated reproductive aging. Oxidative stress (OS) is a potential mechanism behind ovarian toxicity by cyclophosphamide (CPM), the most ovotoxic anticancer drug. An important sensor of OS is SIRT1, a NAD(+)-dependent deacetyla...

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Detalles Bibliográficos
Autores principales: Di Emidio, Giovanna, Rossi, Giulia, Bonomo, Isabelle, Alonso, Gonzalo Luis, Sferra, Roberta, Vetuschi, Antonella, Artini, Paolo Giovanni, Provenzani, Alessandro, Falone, Stefano, Carta, Gaspare, D'Alessandro, Anna Maria, Amicarelli, Fernanda, Tatone, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705900/
https://www.ncbi.nlm.nih.gov/pubmed/29270246
http://dx.doi.org/10.1155/2017/8928604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705900/
https://www.ncbi.nlm.nih.gov/pubmed/29270246
http://dx.doi.org/10.1155/2017/8928604

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