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Molecular Dynamics Simulation Reveals Specific Interaction Sites between Scorpion Toxins and K(v)1.2 Channel: Implications for Design of Highly Selective Drugs

The K(v)1.2 channel plays an important role in the maintenance of resting membrane potential and the regulation of the cellular excitability of neurons, whose silencing or mutations can elicit neuropathic pain or neurological diseases (e.g., epilepsy and ataxia). Scorpion venom contains a variety of...

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Detalles Bibliográficos
Autores principales:	Yuan, Shouli, Gao, Bin, Zhu, Shunyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705969/ https://www.ncbi.nlm.nih.gov/pubmed/29104247 http://dx.doi.org/10.3390/toxins9110354

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