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Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

The adenylate cyclase toxin CyaA is involved in the early stages of infection by Bordetella pertussis, the causative agent of whooping cough. CyaA intoxicates target cells by a direct translocation of its catalytic domain (AC) across the plasma membrane and produces supraphysiological levels of cAMP...

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Detalles Bibliográficos
Autores principales: Voegele, Alexis, Subrini, Orso, Sapay, Nicolas, Ladant, Daniel, Chenal, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705984/
https://www.ncbi.nlm.nih.gov/pubmed/29135925
http://dx.doi.org/10.3390/toxins9110369