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Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
The adenylate cyclase toxin CyaA is involved in the early stages of infection by Bordetella pertussis, the causative agent of whooping cough. CyaA intoxicates target cells by a direct translocation of its catalytic domain (AC) across the plasma membrane and produces supraphysiological levels of cAMP...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705984/ https://www.ncbi.nlm.nih.gov/pubmed/29135925 http://dx.doi.org/10.3390/toxins9110369 |