Cargando…
Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
The adenylate cyclase toxin CyaA is involved in the early stages of infection by Bordetella pertussis, the causative agent of whooping cough. CyaA intoxicates target cells by a direct translocation of its catalytic domain (AC) across the plasma membrane and produces supraphysiological levels of cAMP...
Autores principales: | Voegele, Alexis, Subrini, Orso, Sapay, Nicolas, Ladant, Daniel, Chenal, Alexandre |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705984/ https://www.ncbi.nlm.nih.gov/pubmed/29135925 http://dx.doi.org/10.3390/toxins9110369 |
Ejemplares similares
-
Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion
por: Sotomayor-Pérez, Ana-Cristina, et al.
Publicado: (2014) -
The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro
por: Voegele, Alexis, et al.
Publicado: (2019) -
A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells
por: Voegele, Alexis, et al.
Publicado: (2021) -
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis
por: O’Brien, Darragh P., et al.
Publicado: (2017) -
Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis
por: Cannella, Sara E., et al.
Publicado: (2017)