Ectopic Expression of Snail and Twist in Ph+ Leukemia Cells Upregulates CD44 Expression and Alters Their Differentiation Potential

Philadelphia chromosome-positive (Ph+) leukemia is characterized by reciprocal translocation between chromosomes 9 and 22. The resultant BCR/ABL fusion protein displays constitutive tyrosine kinase activity, leading to the induction of aberrant proliferation and neoplastic transformation. The bone m...

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Detalles Bibliográficos
Autores principales: Kidan, Noa, Khamaisie, Hazem, Ruimi, Nili, Roitman, Shay, Eshel, Elizabeth, Dally, Najib, Ruthardt, Martin, Mahajna, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705997/
https://www.ncbi.nlm.nih.gov/pubmed/29187870
http://dx.doi.org/10.7150/jca.19633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705997/
https://www.ncbi.nlm.nih.gov/pubmed/29187870
http://dx.doi.org/10.7150/jca.19633

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