Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation

A series of bromophenol hybrids with N-containing heterocyclic moieties were designed, and their anticancer activities against a panel of five human cancer cell lines (A549, Bel7402, HepG2, HCT116 and Caco2) using MTT assay in vitro were explored. Among them, thirteen compounds (17a, 17b, 18a, 19a,...

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Detalles Bibliográficos
Autores principales: Wang, Li-Jun, Guo, Chuan-Long, Li, Xiang-Qian, Wang, Shuai-Yu, Jiang, Bo, Zhao, Yue, Luo, Jiao, Xu, Kuo, Liu, Hua, Guo, Shu-Ju, Wu, Ning, Shi, Da-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706033/
https://www.ncbi.nlm.nih.gov/pubmed/29104274
http://dx.doi.org/10.3390/md15110343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706033/
https://www.ncbi.nlm.nih.gov/pubmed/29104274
http://dx.doi.org/10.3390/md15110343

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