AS1041, a Novel Synthesized Derivative of Marine Natural Compound Aspergiolide A, Arrests Cell Cycle, Induces Apoptosis, and Inhibits ERK Activation in K562 Cells

AS1041 is a novel synthesized anthraquinone lactone derivative of marine natural compound aspergiolide A (ASP-A) with new structure skeleton and marked cytotoxicity in cancer cells. To study its cytotoxicity in detail, we evaluated its activity on human K562 chronic myelogenous leukemia cells and in...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Fengli, Qiao, Liang, Chen, Yinghan, Qi, Xin, Liu, Yankai, Li, Dehai, Gu, Qianqun, Li, Jing, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706036/
https://www.ncbi.nlm.nih.gov/pubmed/29113054
http://dx.doi.org/10.3390/md15110346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706036/
https://www.ncbi.nlm.nih.gov/pubmed/29113054
http://dx.doi.org/10.3390/md15110346

Ejemplares similares