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AS1041, a Novel Synthesized Derivative of Marine Natural Compound Aspergiolide A, Arrests Cell Cycle, Induces Apoptosis, and Inhibits ERK Activation in K562 Cells

AS1041 is a novel synthesized anthraquinone lactone derivative of marine natural compound aspergiolide A (ASP-A) with new structure skeleton and marked cytotoxicity in cancer cells. To study its cytotoxicity in detail, we evaluated its activity on human K562 chronic myelogenous leukemia cells and in...

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Detalles Bibliográficos
Autores principales:	Yuan, Fengli, Qiao, Liang, Chen, Yinghan, Qi, Xin, Liu, Yankai, Li, Dehai, Gu, Qianqun, Li, Jing, Liu, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706036/ https://www.ncbi.nlm.nih.gov/pubmed/29113054 http://dx.doi.org/10.3390/md15110346

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