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Kinetics and dissolution of intratracheally administered nickel oxide nanomaterials in rats

BACKGROUND: The toxicokinetics of nanomaterials are an important factor in toxicity, which may be affected by slow clearance and/or distribution in the body. METHODS: Four types of nickel oxide (NiO) nanoparticles were single-administered intratracheally to male F344 rats at three doses of 0.67–6.0 ...

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Detalles Bibliográficos
Autores principales: Shinohara, Naohide, Zhang, Guihua, Oshima, Yutaka, Kobayashi, Toshio, Imatanaka, Nobuya, Nakai, Makoto, Sasaki, Takeshi, Kawaguchi, Kenji, Gamo, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706298/
https://www.ncbi.nlm.nih.gov/pubmed/29183341
http://dx.doi.org/10.1186/s12989-017-0229-x