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A proximity-based graph clustering method for the identification and application of transcription factor clusters

BACKGROUND: Transcription factors (TFs) form a complex regulatory network within the cell that is crucial to cell functioning and human health. While methods to establish where a TF binds to DNA are well established, these methods provide no information describing how TFs interact with one another w...

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Detalles Bibliográficos
Autores principales: Spadafore, Maxwell, Najarian, Kayvan, Boyle, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706350/
https://www.ncbi.nlm.nih.gov/pubmed/29187152
http://dx.doi.org/10.1186/s12859-017-1935-y