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A proximity-based graph clustering method for the identification and application of transcription factor clusters
BACKGROUND: Transcription factors (TFs) form a complex regulatory network within the cell that is crucial to cell functioning and human health. While methods to establish where a TF binds to DNA are well established, these methods provide no information describing how TFs interact with one another w...
Autores principales: | Spadafore, Maxwell, Najarian, Kayvan, Boyle, Alan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706350/ https://www.ncbi.nlm.nih.gov/pubmed/29187152 http://dx.doi.org/10.1186/s12859-017-1935-y |
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