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Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells

BACKGROUND: In vitro and in vivo studies have shown that Zuo Jin Wan (ZJW), a herbal formula of traditional Chinese medicine (TCM), possessed anticancer properties. However, the underlying mechanism for the action of ZJW remains unclear. Various subtypes of 5-Hydroxytryptamine receptor (5-HTR) have...

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Detalles Bibliográficos
Autores principales: Pan, Jielu, Xu, Yangxian, Song, Haiyan, Zhou, Xiqiu, Yao, Zemin, Ji, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706385/
https://www.ncbi.nlm.nih.gov/pubmed/29183322
http://dx.doi.org/10.1186/s12906-017-2006-7