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Sirt1 interaction with active Smad2 modulates transforming growth factor-β regulated transcription
BACKGROUND: The simplicity of Transforming Growth Factor ß (TGFβ) signaling pathway, linear and non-amplified, hardly sustains its variety of responses. This is often justified by the complex regulation showed by Smad proteins, TGFβ signaling intracellular transducers, object of post-translational m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706420/ https://www.ncbi.nlm.nih.gov/pubmed/29187201 http://dx.doi.org/10.1186/s12964-017-0205-y |