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Kavalactone yangonin induces autophagy and sensitizes bladder cancer cells to flavokawain A and docetaxel via inhibition of the mTOR pathway

Consumption of kava (Piper methysticum Forst) has been linked to reduced cancer risk in the South Pacific Islands. Kavalactones are major bioactive components in kava root extracts, which have recently demonstrated anti-cancer activities. However, molecular mechanisms of kavalactones' anti-canc...

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Detalles Bibliográficos
Autores principales: Liu, Zhongbo, Ha, U-Syn, Yu, Ke, Wu, Chunli, Yokoyama, Noriko, Zi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706433/
https://www.ncbi.nlm.nih.gov/pubmed/28959001
http://dx.doi.org/10.7555/JBR.31.20160160