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Kavalactone yangonin induces autophagy and sensitizes bladder cancer cells to flavokawain A and docetaxel via inhibition of the mTOR pathway
Consumption of kava (Piper methysticum Forst) has been linked to reduced cancer risk in the South Pacific Islands. Kavalactones are major bioactive components in kava root extracts, which have recently demonstrated anti-cancer activities. However, molecular mechanisms of kavalactones' anti-canc...
Autores principales: | Liu, Zhongbo, Ha, U-Syn, Yu, Ke, Wu, Chunli, Yokoyama, Noriko, Zi, Xiaolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706433/ https://www.ncbi.nlm.nih.gov/pubmed/28959001 http://dx.doi.org/10.7555/JBR.31.20160160 |
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