cPKCγ‐mediated down‐regulation of UCHL1 alleviates ischaemic neuronal injuries by decreasing autophagy via ERK‐mTOR pathway

Stroke is one of the leading causes of death in the world, but its underlying mechanisms remain unclear. Both conventional protein kinase C (cPKC)γ and ubiquitin C‐terminal hydrolase L1 (UCHL1) are neuron‐specific proteins. In the models of 1‐hr middle cerebral artery occlusion (MCAO)/24‐hr reperfus...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Han, Song, Wang, Shizun, Luo, Yanlin, Zhao, Li, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706506/
https://www.ncbi.nlm.nih.gov/pubmed/28726275
http://dx.doi.org/10.1111/jcmm.13275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706506/
https://www.ncbi.nlm.nih.gov/pubmed/28726275
http://dx.doi.org/10.1111/jcmm.13275

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