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Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism

Both primary hepatocytes and stem cells‐derived hepatocyte‐like cells (HLCs) are major sources for bioartificial liver (BAL). Maintenance of hepatocellular functions and induction of functional maturity of HLCs are critical for BAL's support effect. It remains difficult to assess and improve de...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Chang, Le, Zhai, Jiahui, Wu, Qiao, Wang, Donggen, Wang, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706564/
https://www.ncbi.nlm.nih.gov/pubmed/28557353
http://dx.doi.org/10.1111/jcmm.13225