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MMP‐2 and MMP‐13 affect vasculogenic mimicry formation in large cell lung cancer

Matrix metalloproteinases (MMPs) have critical functions in tumour vasculogenic mimicry (VM). This study explored the mechanisms underlying MMP‐13 and MMP‐2 regulation of tumour VM formation in large cell lung cancer (LCLC). In our study, laminin5 (Ln‐5) fragments cleaved by MMP‐2 promoted tubular s...

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Detalles Bibliográficos
Autores principales: Li, Yanlei, Sun, Baocun, Zhao, Xiulan, Wang, Xudong, Zhang, Danfang, Gu, Qiang, Liu, Tieju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706571/
https://www.ncbi.nlm.nih.gov/pubmed/28766880
http://dx.doi.org/10.1111/jcmm.13283