MMP‐13 deletion decreases profibrogenic molecules and attenuates N‐nitrosodimethylamine‐induced liver injury and fibrosis in mice

Connective tissue growth factor (CTGF) is involved in inflammation, pathogenesis and progression of liver fibrosis. Matrix metalloproteinase‐13 (MMP‐13) cleaves CTGF and releases several fragments, which are more potent than the parent molecule to induce fibrosis. The current study was aimed to eluc...

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Detalles Bibliográficos
Autores principales: George, Joseph, Tsutsumi, Mikihiro, Tsuchishima, Mutsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706575/
https://www.ncbi.nlm.nih.gov/pubmed/28782260
http://dx.doi.org/10.1111/jcmm.13304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706575/
https://www.ncbi.nlm.nih.gov/pubmed/28782260
http://dx.doi.org/10.1111/jcmm.13304

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