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MiR‐29b‐3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN

This study was aimed to explore the role of miR‐29b‐3p and PGRN in chondrocyte apoptosis and the initiation and progress of osteoarthritis (OA). Both miR‐29b‐3p and PGRN were up‐regulated in cartilage tissue from patients with OA. Transfection of miR‐29b‐3p mimic into rat primary chondrocytes and SW...

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Detalles Bibliográficos
Autores principales: Chen, Lingqiang, Li, Qin, Wang, Jing, Jin, Song, Zheng, Hongmei, Lin, Jun, He, Fang, Zhang, Hong, Ma, Sha, Mei, Jian, Yu, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706578/
https://www.ncbi.nlm.nih.gov/pubmed/28609022
http://dx.doi.org/10.1111/jcmm.13237