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Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome (LQTS), which is caused by perturbation of ion channel function, and can lead to fainting, malig...

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Detalles Bibliográficos
Autores principales: Duncan, Gary, Firth, Karl, George, Vinoj, Hoang, Minh Duc, Staniforth, Andrew, Smith, Godfrey, Denning, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706629/
https://www.ncbi.nlm.nih.gov/pubmed/28992755
http://dx.doi.org/10.1089/scd.2017.0172