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Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now a well-established modality for modeling genetic disorders of the heart. This is especially so for long QT syndrome (LQTS), which is caused by perturbation of ion channel function, and can lead to fainting, malig...
Autores principales: | Duncan, Gary, Firth, Karl, George, Vinoj, Hoang, Minh Duc, Staniforth, Andrew, Smith, Godfrey, Denning, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706629/ https://www.ncbi.nlm.nih.gov/pubmed/28992755 http://dx.doi.org/10.1089/scd.2017.0172 |
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