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Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition

Chl1 DNA helicase promotes sister chromatid cohesion and associates with both the cohesion establishment acetyltransferase Eco1/Ctf7 and the DNA polymerase processivity factor PCNA that supports Eco1/Ctf7 function. Mutation in CHL1 results in precocious sister chromatid separation and cell aneuploid...

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Detalles Bibliográficos
Autores principales: Shen, Donglai, Skibbens, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706694/
https://www.ncbi.nlm.nih.gov/pubmed/29186203
http://dx.doi.org/10.1371/journal.pone.0188739