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Chl1 DNA helicase and Scc2 function in chromosome condensation through cohesin deposition
Chl1 DNA helicase promotes sister chromatid cohesion and associates with both the cohesion establishment acetyltransferase Eco1/Ctf7 and the DNA polymerase processivity factor PCNA that supports Eco1/Ctf7 function. Mutation in CHL1 results in precocious sister chromatid separation and cell aneuploid...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706694/ https://www.ncbi.nlm.nih.gov/pubmed/29186203 http://dx.doi.org/10.1371/journal.pone.0188739 |