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Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity

Inositol pyrophosphates have been implicated in a wide range of cellular processes. Inositol hexakisphosphate kinase 1 catalyzes the pyrophosphorylation of inositol hexakisphosphate into inositol 5-diphospho-1,2,3,4,6-pentakisphosphate which is important in numerous areas of cell physiology such as...

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Detalles Bibliográficos
Autores principales: Wormald, Michael, Liao, Gangling, Kimos, Martha, Barrow, James, Wei, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706701/
https://www.ncbi.nlm.nih.gov/pubmed/29186181
http://dx.doi.org/10.1371/journal.pone.0188852