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Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort
The underlying genetic cause of colorectal cancer (CRC) can be identified for 5-10% of all cases, while at least 20% of CRC cases are thought to be due to inherited genetic factors. Screening for highly penetrant mutations in genes associated with Mendelian cancer syndromes using next-generation seq...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706810/ https://www.ncbi.nlm.nih.gov/pubmed/29212164 http://dx.doi.org/10.18632/oncotarget.18596 |