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Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort

The underlying genetic cause of colorectal cancer (CRC) can be identified for 5-10% of all cases, while at least 20% of CRC cases are thought to be due to inherited genetic factors. Screening for highly penetrant mutations in genes associated with Mendelian cancer syndromes using next-generation seq...

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Detalles Bibliográficos
Autores principales: Raskin, Leon, Guo, Yan, Du, Liping, Clendenning, Mark, Rosty, Christophe, Lindor, Noralane M., Gruber, Stephen B., Buchanan, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706810/
https://www.ncbi.nlm.nih.gov/pubmed/29212164
http://dx.doi.org/10.18632/oncotarget.18596