Cargando…

Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort

The underlying genetic cause of colorectal cancer (CRC) can be identified for 5-10% of all cases, while at least 20% of CRC cases are thought to be due to inherited genetic factors. Screening for highly penetrant mutations in genes associated with Mendelian cancer syndromes using next-generation seq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raskin, Leon, Guo, Yan, Du, Liping, Clendenning, Mark, Rosty, Christophe, Lindor, Noralane M., Gruber, Stephen B., Buchanan, Daniel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706810/ https://www.ncbi.nlm.nih.gov/pubmed/29212164 http://dx.doi.org/10.18632/oncotarget.18596

Ejemplares similares

Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry
por: Ward, Robyn L., et al.
Publicado: (2013)

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort
por: Rosty, Christophe, et al.
Publicado: (2016)

Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome)
por: Buchanan, Daniel D, et al.
Publicado: (2014)

Disclosing genetic research results: experiences of the Colon Cancer Family Registry
por: Keogh, Louise, et al.
Publicado: (2011)

Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry
por: Jiang, Xuejuan, et al.
Publicado: (2013)

Clinical verification of genetic results returned to research participants: findings from a Colon Cancer Family Registry
por: Laurino, Mercy Y., et al.
Publicado: (2017)

The relationship between the BRAF p.V600E mutation and a family history of CRC in the early-onset CRC cases from the Australasian Colon Cancer Family Study
por: Buchanan, DD, et al.
Publicado: (2012)

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer
por: Shiovitz, S, et al.
Publicado: (2014)

Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome
por: Dashti, S. Ghazaleh, et al.
Publicado: (2019)

Risks of cancers for carriers of monoallelic MUTYH mutation with a family history of colorectal cancer
por: Win, Aung K, et al.
Publicado: (2011)

Risk of colorectal cancer for carriers of a germline mutation in POLE or POLD1
por: Buchanan, Daniel D., et al.
Publicado: (2017)

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes
por: DeRycke, Melissa S., et al.
Publicado: (2017)

Colorectal cancer and self-reported tooth agenesis
por: Lindor, Noralane M, et al.
Publicado: (2014)

Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry
por: Scott, Cameron M., et al.
Publicado: (2016)

Germline miRNA DNA variants and the risk of colorectal cancer by subtype
por: Lindor, Noralane M., et al.
Publicado: (2016)

Serrated Polyposis: An Enigmatic Model of Colorectal Cancer Predisposition
por: Rosty, Christophe, et al.
Publicado: (2011)

Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome
por: Win, Aung Ko, et al.
Publicado: (2015)

Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes
por: Lindor, Noralane M., et al.
Publicado: (2016)

Risk of breast cancer in Lynch syndrome: a systematic review
por: Win, Aung Ko, et al.
Publicado: (2013)

Colorectal cancer in hyperplastic polyposis syndrome: In search of the polyp of origin
por: Rosty, Christophe, et al.
Publicado: (2011)

The Mucin Family of Proteins: Candidates as Potential Biomarkers for Colon Cancer
por: Cox, Kristin E., et al.
Publicado: (2023)

DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer
por: Joo, Jihoon E., et al.
Publicado: (2021)

A mosaic pathogenic variant in MSH6 causes MSH6-deficient colorectal and endometrial cancer in a patient classified as suspected Lynch syndrome: a case report
por: Walker, Romy, et al.
Publicado: (2023)

Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
por: Dienstmann, R., et al.
Publicado: (2017)

Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer
por: Gylfe, Alexandra E., et al.
Publicado: (2013)

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers – the advantage of more extensive surgery
por: Parry, Susan, et al.
Publicado: (2011)

Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome
por: Donahue, Timothy F., et al.
Publicado: (2018)

Reduced expression of deleted colorectal carcinoma (DCC) protein in established colon cancers.
por: Goi, T., et al.
Publicado: (1998)

Quality of Life and Mortality of Long-Term Colorectal Cancer Survivors in the Seattle Colorectal Cancer Family Registry
por: Adams, Scott V., et al.
Publicado: (2016)

Unique obstacles to establishing thyroid cancer registries
por: Pearce, Elizabeth N., et al.
Publicado: (2016)

PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival
por: Rosty, Christophe, et al.
Publicado: (2013)

A study of cancer risks in relatives of patients with serrated polyposis
por: Win, AK, et al.
Publicado: (2012)

Body Mass Index, sex, non-steroidal anti-inflammatory drug medications, smoking and alcohol are differentially associated with World Health Organisation criteria and colorectal cancer risk in people with Serrated Polyposis Syndrome: an Australian case-control study
por: Anthony, Emma, et al.
Publicado: (2022)

A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study
por: Dong, Xinyuan, et al.
Publicado: (2020)

Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario
por: Choi, Yun-Hee, et al.
Publicado: (2009)

Meat intake, cooking methods, dietary carcinogens, and colorectal cancer risk: findings from the Colorectal Cancer Family Registry
por: Joshi, Amit D, et al.
Publicado: (2015)

Associations of Height With the Risks of Colorectal and Endometrial Cancer in Persons With Lynch Syndrome
por: Brouwer, Jesca G M, et al.
Publicado: (2020)

Birt-Hogg-Dube syndrome presenting as multiple oncocytic parotid tumors
por: Lindor, Noralane M, et al.
Publicado: (2012)

Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome
por: Clendenning, Mark, et al.
Publicado: (2013)

Colorectal Tumour Microsatellite Instability Test Results: Perspectives from Patients
por: Lindor, Noralane M, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_24u802u7r3m4ili0mp5sj7cb4s