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Assessment of pancreatic neuroendocrine tumor cytologic genotype diversity to guide personalized medicine using a custom gastroenteropancreatic next-generation sequencing panel

BACKGROUND: Recent genetic studies have highlighted that alterations in MEN1, chromatin remodeling genes, and mammalian target of rapamycin (mTOR) pathway genes are the most frequent molecular events identified in pancreas neuroendocrine tumors (pNETs). The prognostic or predictive impact of these b...

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Detalles Bibliográficos
Autores principales: Gleeson, Ferga C., Voss, Jesse S., Kipp, Benjamin R., Kerr, Sarah E., Van Arnam, John S., Mills, John R., Marcou, Cherisse A., Schneider, Amber R., Tu, Zheng Jin, Henry, Michael R., Levy, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706811/
https://www.ncbi.nlm.nih.gov/pubmed/29212165
http://dx.doi.org/10.18632/oncotarget.18750